Evaluate the efficiency of Antigen 60 (A60) protein from BCG strain of Mycobacterium bovis as a diagnostic antigen
نویسندگان
چکیده
منابع مشابه
Immunological analysis of the components of the antigen complex A60 of Mycobacterium bovis BCG.
The antigen complex of A60 of Mycobacterium bovis BCG was analyzed by different immunological techniques to assess its relevance to tuberculosis and the involvement of its components in the immune reactions elicited in humans by tuberculous infection. A60 is composed of about 30 components, of which 8 were identified by available monoclonal antibodies (lipoarabinomannan, a glycolipid, and prote...
متن کاملPURIFICATION AND MOLECULAR ANALYSIS OF BCG ANTIGEN 60
Tuberculosis remains as an important socioeconomical and medical problem throughout the world and especially in Iran. Early and timely diagnosis of pulmonary and extrapulmonary tuberculosis is vital to initiate prompt treatment. Current diagnostic methods are either slow or lack enough sensitivity or specificity. Several mycobacterial antigens are involved in the complex interaction with t...
متن کاملارزیابی کارایی پروتئین A60 باکتری مایکوباکتریوم بوویس سویه BCG به عنوان پادگن تشخیصی
Tuberculosis is the most common infectious diseases. Current diagnostic methods are either slow or lack enough sensivity or specificity. Several mycobacterial antigens are involved in the complex interaction with the immune system of the host. They can be helpful for mycobacteria diagnosis. Antigen 60 (A60) is thermostable antigen found in Mycobacterium bovis and Mycobacterium tuberculosis...
متن کاملThe etiologic agents of leprosy and tuberculosis share an immunoreactive protein antigen with the vaccine strain Mycobacterium bovis BCG.
The amino acid sequences of the 65-kilodalton antigens of Mycobacterium leprae, Mycobacterium tuberculosis, and Mycobacterium bovis BCG display greater than 95% homology.
متن کاملProduction of MPT-64 recombinant protein from virulent strain of Mycobacterium bovis
Tuberculosis (TB) is a zoonotic infectious disease common to humans and animals which has been caused by a rod shaped, acid fast bacterium, called Mycobacterium bovis. The rapid and sensitive detection is a great challenge for TB diagnosis. The virulent strains of Mycobacterium tuberculosis complex (MTBC) have 16 different regions of difference (RD) in their genome which encode some important a...
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ژورنال
عنوان ژورنال: International Journal of Mycobacteriology
سال: 2016
ISSN: 2212-5531
DOI: 10.1016/j.ijmyco.2016.10.022